Advance of whole brain radiotherapy irradiation of hippocampus in the treatment of small cell lung cancer / 实用肿瘤学杂志

About 15% to 20% of patients with small cell lung cancer(SCLC)have brain metastases at the time of initial di-agnosis,and more than 80% of patients eventually develop brain metastases. Whole brain radiotherapy(WBRT) is the standard treat-ment for brain metastases in lung cancer. Whole brain prophylactic irradiation(PCI)is an effective treatment for preventing brain me-tastases in SCLC. With the improvement of treatment technology and the standard of treatment,the survival of SCLC patients is pro-longed. The use of spiral tomography(TOMO) technology for hippocampal-protected WBRT in PCI or brain metastasis can reduce neurocognitive impairment and improve the life quality of patient.